The Role of Endurance and Stamina in Exercising

Josh Beaty

The Role of Endurance and Stamina in Exercising

March 14, 2019

What is it in our muscles that leads to enhanced endurance and stamina? This goes back to HOW exactly our muscles receive fuel. 

Muscles receive energy in four main steps: the first few seconds use stored ATP within the cell, and then the next few use creatine phosphate stores to provide ATP. Once that has been used glycogen stores in the muscle can be utilized (your non-oxygen energy stores). Lastly, aerobic respiration (ATP produced using oxygen) takes over. 

When it comes to intense exercise, glycogen is the most valuable source of energy. Exercises like weight training, sprinting, intense cycling, and other anaerobic activities rely on those glycogen stores for usable energy. Anaerobic exercise is practiced by athletes for strength, speed, and power, and to build muscle mass.

With these exercises, you are working at such high intensity that your cardiovascular system can't deliver oxygen to your muscles fast enough, note the meaning “without oxygen”. For this reason, anaerobic exercises can only last for short periods at a time or as long as there is available glycogen to be used as energy. The problem occurs when that fuel supply runs out, and not being replenished. 

Blood glucose is stored as glycogen in the muscle. Glycogen is the preferred fuel for muscle function during that intense or anaerobic exercise. Glycogen is a chain of glucose molecules that muscles and liver use to store energy.

As mentioned earlier, muscles need glucose to create energy (ATP) in order to function. Yet, exercise induces inflammation in the muscle membrane which disrupts the supply of glucose into the muscle to replenish used glycogen. In skeletal muscle, binding of insulin to the insulin receptor allows glucose to enter the muscle cell.

Once glucose enters the cell, it can either be converted to ATP and used for energy or stored as glycogen for later. Unfortunately, inflammation decreases insulin receptor sensitivity on the muscle membrane and if that receptor is not triggered, glucose does not move into the cell and energy cannot be supplied to the muscle. Due to this, endurance products should consider lowering muscle inflammation and take glycogen stores into consideration when designing their endurance and stamina formulas. 

ActiGin® is ideal for improving stamina because it addresses all of these concerns. ActiGin® is a blend of highly purified and fractionated Panax notoginseng and Rosa roxburghii extracts using a proprietary pharmaceutical extraction and processing technology available only from NuLiv Science.

Our studies have found decreases muscle inflammation, making it easier for glucose to enter the muscle and replenish glycogen stores for use. ActiGin® reduces inflammation on the muscle membrane where the insulin receptor and glucose transport channel are located to increase the insulin receptor sensitivity so glucose inflow is not interrupted. 

Stamina is then positively affected by ActiGin® as it works to supply the muscle with more energy and reduce the problematic inflammation that is brought on by intense exercise. ActiGin® works with the body to achieve better muscle function leading to improved stamina during workouts. 


If you'd like to learn more about ActiGin® please contact us below and one of our business development representatives will be happy to connect with you: