ABMPrime™ – A NuLiv Science High-Quality Agaricus blazei murill Mushroom
Agaricus blazei murill, like many mushrooms, is a low-calorie food, high in vitamins, minerals and amino acids. It’s also unusually high in protein and carbohydrate and has high levels of a compound called beta glucans.
NuLiv Science provides both a fruiting body and a mycelium version of ABMPrime™ by either a proprietary water fermentation or extraction process. ABMPrime™ is guaranteed to the standardized bioactive compound in our COA (certificate of analysis) validated by UV Spectra assay, for example, 40% polysaccharides.
Furthermore, ABMPrime™ is tested for heavy metals, pesticides, and residues, and many microbiological counts above and beyond the standard total plate count, total mold & yeast, to include E. Coli, Salmonella, Enterobacteriaceae, Staphylococcus aureus performed by our own advanced testing labs and international labs, such as NSF and Eurofins.
We ensure our ABMPrime™ has the exact potency per COA and the lowest heavy metals, pesticide residues, and microbiological counts and the safest Agaricus blazei murill mushroom in the market.
Request a product fact sheet and technical product specifications here.
Promoting vitality and energy | 2,000 YEARS OF HERBAL HEALTH
CordycepsPrime™ is a proprietary Cordyceps sinensis extract produced by a pharmaceutical extraction and formulation process available only from NuLiv Science. Nuliv Science’s proprietary fermentation technology enables CordycepsPrime™ to contain the highest levels and most consistent bioactives, as confirmed by in-house and third-party laboratory analysis (HPLC and UV).
CordycepsPrime™ contains guaranteed Cordycepic acid (d-mannitol) of 8% or greater, verified by monosaccharide HPLC column. We also guarantee Adenosine 0.3% or greater by HPLC, as well as the lowest heavy metals and zero pesticide residues (per SGS assays of over 140 residues) of all commercially available Cordyceps (wild crafted, solid culture, organic, liquid culture, fermentation).
Cordyceps sinensis has been used over 2,000 years in China to promote vitality, energy, and endurance, cardiovascular, respiratory, and adrenal health.* There are over 30 large human trials conducted in China alone, in addition to many in vitro, and in vivo studies.
Nuliv Science’s proprietary fermentation technology uses specific carbohydrates, soybean extracts, and a special blend of trace elements, in addition, other proprietary ingredients as a growth medium. Additionally, specific temperature and Ph parameters are maintained through various stages of the fermentation process to consistently produce the highest quality Cordyceps.
Our PhytoMonitor™ Quality Assurance System guarantees CordycepsPrime™ to meet stringent quality standards.
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Maitake mushroom is a fungi from the Grifolafrondosa species. They are also known as Sheep’s Head, Hen-of-the-Woods, Ram’s Head, and other names. Maitake is the mushroom’s Japanese name. It means “dancing mushroom.” This mushroom grows in clusters at the base of trees, especially oak trees. Grifolafrondosa is used in both Japanese and Traditional Chinese Medicine (TCM) to help support the normal balance of body systems and support a healthy immune system.* This mushroom is also frequently eaten because of its pleasing flavor and texture, especially in Japan.
Maitake mushrooms are sold in health food stores around the world and online at websites that sell herbs, especially Chinese or Asian herbs. They typically grow at the base of the same trees for years, and they can be very large when they are full grown. Maitake can grow to 50 pounds in Japan. Maitake mushrooms have many minerals such as potassium, magnesium, and calcium. They are also full of fibers and amino acids and various vitamins such as D1, B2, and niacin.
Reishi mushroom is a part of the Ganoderma lucidum family.
Regarded as one of the most vital herbal medicines in China for centuries, Reishi mushrooms are used for many purposes ranging from immune-related concerns to promoting proper energy levels. It is also used as a sports enhancer in parts of China. The active ingredient in the fungus is triterpenoids. Reishi is generally not eaten whole or raw. It is usually made into tea or taken as a powder mixed into a beverage or drink mix powder.
Coriolus Mushroom (Coriolus versicolor) 30% is a fungus that has been used for many centuries in Traditional Chinese Medicine. Generally, the Coriolus mushroom extract is viewed in the Traditional Chinese Medicine practice as an immune system strengthener.* Studies have suggested that the mushroom can be useful as a dietary supplement to help individuals maintain a healthy body.*
Most commonly, users prepare Coriolus mushroom as a strong tea, or they take it in capsule form or as an extract, in dosages ranging from 1-9 grams per day.
Wulinshen, or Xylaria Nigripes, is a fungus found in some of most inhospitable places on earth. Located about a yard underground in the Odontotermes formosanus termite nest, Wulinshen is medium brown in color. Wulinshen serves as a primary source of food for these termites, and as a nutritional storehouse, it is well suited to this purpose. In addition to being rich in carbohydrates and protein, Wulinshen boasts an impressive slate of essential amino acids, vitamins, minerals, trace elements, and glycoproteins. But Wulinshen is far more than a food source for these termites.
Human clinical studies have demonstrated that Wulinshen may aid in regulating, supporting and promoting healthy human endocrine, immune, digestive, and metabolic functions.* Researchers have been most intrigued with Wulinshen’s potential to aid in normalizing sleep, mental sharpness, and cognitive function.*
Wulinshen contains a unique combination of ‘deep-sleep’ nutrients that research has shown of promoting deeper sleep and calmness in the mind.* Because of this, Wulinshen is useful for safely inducing restful, deep sleep without the addictive or drowsy side-effects often associated with prescription sleep aids. Wulinshen contains glutamic acid, gamma-aminobutyric acid (GABA) and glutamate decarboxylase, all of which are known to assist in the uptake of GABA by specific brain cell receptors that exert a mild tranquilizing effect on the central nervous system.*
In pharmacological studies, elevated levels of glutamic acid and GABA have demonstrated to upregulate the binding affinity of GABA receptors in the brain in subjects in treatment groups. Furthermore, the activity of glutamate decarboxylase (GAD) was also increased in these subjects, indicating that Wulinshen possesses the ability to enhance the uptake of glutamic acid and GABA into the brain to activate GABA receptors, which may result in promoting normal deep sleep and mood-uplifting effects.
Request a product fact sheet and technical product specifications for Wulinshen here.
A NuLiv Science proprietary Gynostemma pentaphyllum extract | 98% Gypenosides
A member of the gourd family that grows in southern China, 16 species and 3 variations of Jiaogulan have been discovered and documented so far. It is relatively new to the list of adaptogens. According to recent studies, Jiaogulan contains nearly four times as many saponins as Panax ginseng. These saponins, known as gypenosides, are similar to the ginsenosides and panaxosides found in Asian ginseng. Preliminary studies also suggest Jiaogulan may have even more powerful regulatory effects on a number of body systems than does Asian ginseng.
Jiaogulan has traditionally been grown in the remote mountainous regions in South Central China, where the inhabitants enjoy longevity and good health.* In ancient times, Jiaogulan was consumed as the sole source of nutrient during a famine. Later, this herb became a popular dietary botanical and tea known for its refreshing taste and its health-promoting benefits.* Jiaogulan has often being referred to as the most powerful adaptogenic Chinese herb.
Like all herbal products, the growing environment plays a very important role in the quality of the herb. NuLiv Science analyzed the gypenosides content of Jiaogulan grown in seven major production regions in China and found that Jiaogulan grown in one region contains the highest gypenosides. NuLiv also analyzed the content of trace elements in Jiaogulan from various regions, the results showed that Jiaogulan from this same region contains more than 23 trace elements, thirteen of them are essential to human health (Fe, Zn, Cu, Mn, Co, Cr, Mo, Se, Ni, V, Sr, Si, B). NuLiv Science chooses to work only with Jiaogulan grown in this region.
PROPRIETARY EXTRACTION PROCESS
NuLiv Science uses a proprietary “Resin Adsorption” technique to extract the beneficial gypenosides in Jiaogulan from the freshest and premium crop from this particular region to produce a product of high purity and yield. During the extraction process, the Rb1 gypenoside is monitored at each step of the process to assure the quality of the finished product meets ours and customer’s specifications. NuLiv Science’s Jiaogulan is a standardized natural product.
Chemical analysis shows JiaogulanEx™ has:
Jiaogulan is a versatile adaptogen ingredient that may:
The FDA has not evaluated these statements.
This product is not intended to diagnose, treat, cure or prevent disease.
A NuLiv Science Proprietary Rosa Roxburghii Fruit Extract
Rosa roxburghii, also known as ‘Chestnut Rose’, ‘Burr Rose’, and ‘Chinquapin Rose’ is a low growing fruit tree native to some small remote regions in Southern China. It was named after William Roxburgh who was an assistant surgeon with the East India Company and the first westerner to introduce this tree to the western world.
R. Roxburghii fruit is oval or spindle-shaped, orange colored, heavily covered with soft or hard prickles. It is rich in vitamin C, phenols and abundance of other vitamins and flavonoids, trace elements as well as amino acids. The natural fruit contains 46 times more vitamin C than oranges and 120 times more flavonoids than many vegetables and 10-60 times more than that of other fruits.
NuLiv’s lab assays and in-vitro studies have demonstrated that R. Roxburghii fruit extract may produce potent SOD-Like activity in human cells that may be capable of quenching superoxide free radicals. This unique property distinguishes R. Roxburghii from the S.O.D found in other plants which is mostly destroyed by stomach acids.
RosaEx™ contains extremely high content of Vitamin C (3% or greater), Phenols (10% or greater) and Flavonoids derived naturally from the fruit itself as well as Vitamins A, B1, B2, D, E and trace elements.
RosaEx™ also contains compound(s) that produces potent SOD-like activity in the human body (see section 5) that can neutralize one of the most destructive free radical, superoxide. What is most unique about this compound(s) is that it is immune to the destruction of the acidic stomach fluid while the SOD in most plants is not.
Osteosine™ is a proprietary all natural plant derived bone health nutraceutical complex developed by NuLiv Science. Osteosine™ has shown in NuLiv’s one in-vitro and two in-vivo studies to:
Osteoblasts build new bone tissue and osteoclasts remove old bone tissue by removing its mineralized matrix and breaking up the organic bone (organic dry weight is 90% collagen). In NuLiv’s in-vitro study, Osteosine™ has shown to increase the osteoblasts, a mononucleate cell, by 20%.* More osteoblasts build more new bone tissue to replace lost old bone tissue. These observations were validated through biomarkers such as ALP, IL-1, IL-6, OPG, RANK, that have been associated with their presence and activities (5).
In NuLiv’s two in-vivo studies, the PO (post-ovariectomized) and the RA models (Retinoic Acid Induced), Osteosine™ has shown to increase serum calcium, serum tartrate-resistant acid phosphatase, serum osteocalcin, bone alkaline phosphatase, bone ash, bone calcium, bone phosphorus contents in the treatment versus the control groups.* More importantly, the structural strength of bone that is critical for bone’s ability to withstand fracture, the trabecula surface, average surface percent and weight of trabecula, were also improved (6).*
NuLiv has received over a dozen DEXA lab reports in the past years from customers who have purchased and taken Osteosine™ and sent in these reports as a requirement to receive free Osteosine™ product described in NuLiv’s incentive program. This Osteosine™ contains the Osteosine™ with small amounts of minerals and vitamin D3 and K2 added. Table 1 below summarizes the information given in table 2 that contains tabulated original data in these reports.
Table 1. Summary of 15 cases of laboratory Data
|Area||NO. of subject||Mean (%)||S.D. (%)||Avg. Month on Osteosine™|
|Lumbar (mostly L1 through L4)||12||+7.43%||+9.03%||11.5|
|Femur (left, right, neck, tourchanter)||14||+2.04%||+5.73%||15.5|
Table 2. Summary of original data tabulated from customers DEXA lab reports
|Seq #||Init.||Age||Sex||Date||Loc.||BMD (g/cm2)||Date||BMD (g/cm2)||Time on Osteosine™ (months)||change||Remark|
|Left femur neck||0.832||0.826||-0.7%|
|Left femur neck||0.443||0.497||+11.9%|
|Left femur neck||0.628||0.655||+4.2%|
|Right femur neck||0.703||0.741||+5.3%|
|Left femur troch.||0.485||0.540||+11.2%|
|Right femur troch.||0.533||0.543||+1.9%|
|Total left femur||0.625||0.663||+6.0%|
|Total right femur||0.670||0.680||+1.6%|
|Right femur neck||0.676||0.644||-4.7%|
|Right femur troch.||0.495||0.471||-4.9%|
|Total right femur||0.659||0.635||-3.6%|
|Right femur neck||0.809|
The human laboratory data presented in table 1 correspond to NuLiv’s in-vitro and two in-vivo studies. Even though the results are not from a controlled human clinical trial, it may be reasonable to suggest that the lifestyle, diet, supplement, and physical activities are about or approximately the same before, during, and after the Osteosine™ supplementation periods. That is to say, the subjects who voluntarily offered these lab reports stayed with the same diet, taken about the same amount of calcium and vitamin D3, and engaged in the same level of physical activities, that included walking and weight-bearing exercises.
Osteosine™ has been sold online, in health stores and through mail catalogs worldwide since 2004.
NuLiv Science in-vitro study suggested that Osteosine™ may alter the bone “remodeling” process by enhancing the activity of osteoblasts and decreasing the activity of osteoclasts so more new bone tissues are built to outpace the number of old bone tissues that are removed.*
NuLiv Science two in-vivo studies further demonstrated that Osteosine™ increased the BMD and trabecula surface area and width in both the menopause/post-menopause and externally induced acute osteoporosis models.*
The human laboratory data, although collected from customers that are not part of a controlled human study, nevertheless represents a set of true factual data that approximate what a controlled and well design human experimental design will possibly yield.
One interesting note from these lab reports indicated some of these customers were formerly on osteoporosis drugs and discontinued taking these drugs either because of side effects or none effectiveness of these drugs.
The contents of this publication have not been evaluated by the Food and Drug Administration. They are not presented here to provide information and advice that in any way is intended to diagnose, treat, cure or prevent disease.
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