16 in-vitro and 8 in-vivo studies

Published in

  • The Journal of Agricultural and Food Chemistry
  • Molecular Nutrition & Food Research
  • Scientific Reports

Patents US8197860 B2, US 13/444765,

US 13/444770, US 12/424193 US 12/345218

GRAS/NDI self-affirmed

NPN 80079287

Pennies per serving

Colon Illistrations


AstraGin® is a 100% natural compound composed of highly purified saponins isolated from the Astragalus membranaceous and Panax notoginseng plant.

AstraGin® holds a US patent for “Method of enhancing nutrient absorption” as well as multiple international patents.

In multiple pre-clinical and in-vivo studies, AstraGin® has demonstrated it may help support the absorption of many amino acids and peptides, fatty acids, vitamin and phyto nutrients, gut lining health (epithelial cell) and under layer (lamina propria) damaged by inflammation.*

Supplementing with AstraGin® can help provide a favorable environment for friendly bacteria to grow and strengthen the immune functions.

Studies to date are promising, demonstrating a reduction in inflammation in gut under lining (lamin propria) where many immune cells are located.*


  • Protein
  • Sports Nutrition
  • Wellness*
  • Anti-Aging*
  • Gut Health (together with probiotics)*
  • Immune health*


Gras Affirmed
InformedChoice Sport Certified


Marker compounds: Total saponins greater than or equal to 1.5%
Solubility: Soluble in water
Color: Light beige
Odor: Characteristic
Taste: Slightly bitter
Appearance: Fine granular powder
pH: 6.9-7.0 (1g in 100mL water)
Shelf life: 36 months
Preservatives: None


The human gut has a huge impact on the entire health of the body. A healthy gut contributes to better absorption, a healthy gut ecosystem, stronger immune functions, heart health, brain health, improved mood, healthy sleep, and more.

Nutrients in the foods, once digested, may enter the human body from the gut lumen by passive diffusion and osmosis. But many nutrients such as amino acids, do require active transporters located on the intestinal epithelial cell membrane to transport them from the gut lumen to circulation, such as SGLT1 for glucose absorption. 

These active transporters are activated by mRNA. Disruption of normal barrier function is a fundamental factor in inflammatory bowel disease, which includes increased epithelial cell death, modified mucus configuration, altered tight junctions, along with a decreased expression of antimicrobial peptides.

Gut microbiota is a dynamic “organ” of critical importance for human health. In healthy conditions, the symbiotic microorganisms in the intestinal tract participate in the normal nutrient metabolism and immunity regulation of the host. Gut mucosal integrity is absolutely important for the adhesion and growth of gut microbiota.

The lymphoid elements of the gut comprise organized lymphoid tissues such as the Peyer’s patches (PP), and the mesenteric lymph nodes (MLN). The effector sites of the intestine are the mucosal epithelium and underlying lamina propria (LP). Here there are many different immune cells including activated T cells, plasma cells, mast cells, dendritic cells, and macrophages. Inflamed intestinal epithelial cell and lamina propria reduce these immune cells and weaken the immune functions.

Nutrition at Peak Performance

We spend countless hours researching superfoods and new herb extracts to give us the physical appearance, sports performance, and beauty enhancements we are looking for.

We consume raw this, cold pressed that, herb extracts and dietary supplements.

Do we ever ask ourselves: are we getting the most nutrients from our nutrition? Just because we eat something “healthy,” does not mean our body is getting all the nutrients from our healthy superfood or supplement.

Is There a Way to Make My Superfood More Super?

How do we get as much glucosamine as we can into our knees?

We take curcumin for its numerous health benefits, but how do we get the most out of our curcumin products?

Protein shakes have been the craze for decades. We all have a shaker or two in our cupboards, but how exactly are we getting the protein from the shake and into our muscles?

It really boils down to how bioavailable these nutrients are to our bodies, and how bioavailable our body narrows down to absorption.

Once we consume a superfood or supplement, it is broken down into smaller building block. The digested building blocks move down our intestines and then are absorbed into the bloodstream.

90% of our body’s absorption occurs in the small intestine. This is where carrier molecules (think delivery trucks taking foods to loading docks) transport various nutrients into our bloodstream which is then delivered to cells, tissues, muscles, and organs in our body.

If 90% of the nutrients are absorbed in this key area, it is vital for our absorption aka our body’s bioavailability to be at its best.

How we digest and absorb determines how much nutrients in what we eat actually get to the trillion cells in our body.

Most nutrients are absorbed by helpers or carrier molecules (transporters) to get them through the intestinal wall out into general circulation (bloodstream) so they can be distributed to the entire body.

This is how our favorite superfood or supplement can have the most effect on our bodies.

Absorption can be impaired by diets, medication, stress, pollution, and a sedentary lifestyle. Consequently, absorption plays a critical role in the final bioavailability of nutrients in the human body and has a great impact on our health.

The healthiest diet does not equate to the most nutritious diet if you are not getting the most nutrients from your nutrition.