Verbasnol is an advanced age-defying botanical derived from Rehmannia glutinosa to nourish the skin with antioxidants. 


Verbascoside has been studied for its potential to support a reduction in the expression of the pro-inflammatory chemokine IL-8, which may contribute to anti-inflammatory activity in skin cells.*


Verbascoside has been researched for its potential antioxidative properties, which may help in neutralizing free-radical species associated with oxidative stress in human skin aging.*


Supports skin protection from the potential harm of intense UV rays and helps maintain skin radiance.*

Verbasnol™ plant composition

Rehmannia glutinosa (leaf)


What Makes Verbasnol™ Unique? Just About Everything.

Numerous environmental factors, general skin health challenges, and overall protection contribute to what makes this an incredible botanical.

The antioxidants within Verbasnol replenish the skin and sweep away the adverse effects of sunlight, oxidative stress, and dryness while maintaining skin hydration and elasticity.

Verbasnol™ can be used in many products, but it’s most useful in:






Verbasnol™ validated by HPLC

An Effective Verbascoside

Verbasnol™ is validated by HPLC as a true verbascoside (a caffeoyl phenylethanoid glycoside (C29H36O15)).

The Science Behind Verbasnol:
Associated Effects Based on Research Findings

A verbascoside is characterized as an effect scavenger of biologically active free radicals and an inhibitor of lipid peroxidation. Fewer free radicals invading the skin layers mean healthier, smooth, and lustrous skin.

In research studies, verbascoside has shown to be effective for:

  • Anti-Acne*
  • Anti-Aging*
  • Anti-Erythema*
  • Anti-Inflammatory*
  • Anti-Malassezia*
  • Anti-Oxidant*
  • Collagenase Inhibitor*
  • Sebum Regulating*
  • Tyrosinase Inhibitor*

In a study on human fibroblast cells (the cells that comprise your top layer of skin), verbascoside “possessed significant photoprotective activities, reducing MMP and IL-6 levels while improving type-I procollagen synthesis”.


How Verbascoside Works

Propionibacterium acnes (P. acnes) is associated with acne lesions and leads to cutaneous inflammation. Verbascoside has anti-acne activity by inhibiting P. acnes growth. Verbascoside has been shown to decrease the pro-inflammatory chemokine IL-8 expression to exert anti-inflammatory activity on skin cells.

Furthermore, verbascoside may inhibit Malassezia furfur (a lipophilic yeast) growth that is implicated in numerous skin irritations, including pityriasis versicolor, seborrheic and atopic dermatitis, dandruff, and folliculitis.

Verbascoside exerts a remarkable antioxidative property by scavenging the free-radical species that are implicated in oxidative stress in human skin aging. Furthermore, the glycoside also inhibits the production of tyrosinase that catalyzes the production of melanin to darken the skin. It’s also noteworthy to mention that verbascoside may inhibit the 5α-reductase activity of skin sebum production to control androgen homeostasis in human skin.

Consumer Shifts and Marketing Opportunity: From Old to Young

For years, many nutricosmetics consumers consisted of the older generation. But companies are noticing untapped
opportunities among younger populations. A study reveals that buyers who bought skincare items the most
among all beauty products in the US in 2021 were as follows**:

• Generation Z: 40%
• Millennials: 40%
• Generation X: 31%
• Boomers: 31%

Skincare routines are becoming the norm at an increasingly young age in an effort to delay the signs of aging.
Younger populations like millennials are focused on using skincare products long before skin issues would
normally occur, which explains why millennials lead the consumer demographic for natural skincare supplements.
Research finds that about 40% of US millennials had already purchased natural skincare products, and 34% were
planning to do so.**

Men Care About Skin Health Too!

The market is awash with skincare products for women because after all, women are known to go the extra mile
to look beautiful and appealing. But recent years have witnessed a surprising shift: More men are also going that
extra mile. Prima & Prep’s Men Grooming 2019 survey revealed that around 89.5% of men care about skin health,
and 35.8% use anti-aging and skin-nourishment products daily.***

When it comes to men, marketing and manufacturing companies tend to refrain from using the term beauty
products, but awareness about skin health for men is rising. For example, creams and sunscreen lotions are gaining
major traction because of the increasing awareness of the adverse effects of exposure to the sun.

** Fortune Business Insights, 2021, The Global Skincare Market Is Projected to Grow from $100.13 Billion
in 2021 to $145.82 Billion in 2028 at a CAGR of 5.52% in Forecast Period, 2021-2028… Read More at:,

*** “Men Have Poor Grooming Habits (2022 Survey).” Prim and Prep, Prim and Prep, 22 Apr. 2022,