Senactiv® is the first senolytic sportsceutical that elevates exercise endurance, recovery, and energy while supporting senescent cell clearance and new muscle cell generation during high-intensity exercise.
MECHANISM OF ACTION
HEALTH BENEFITS
- Enhances exercise endurance*
- Increases muscle energy during exercise*
- Accelerates recovery after exercise*
- Stimulates muscle cell renewal*
SENACTIV® SUPPORTS REPLACEMENT OF SENESCENT CELLS WITH NEW MUSCLE CELLS FOR ENHANCED EXERCISE PERFORMANCE
Citrate Synthase Activity (%)
Relative Glycogen Accumulation Rate (%)
Inflammatory & Oxidative Biomarkers (%)
Senescence Clearance (%)
New & Regenerative Muscle Cells (%)
HOW SENACTIV® WORKS
Muscle, like all tissue, is made of a network of cells. These cells are constantly dividing and regenerating to maintain the health and function of the tissue. Although, at a certain point, these cells may stop regenerating and become senescent. This means the cell is no longer a functioning part of the muscle tissue, but instead of “dying” and being replaced by a healthy cell, it stays put taking up space where a healthy and contributing cell could be. The higher density of senescent cells in a tissue, the lower the tissue can perform.
Taking Senactiv® before intense physical activity or exercise helps to activate the body’s pathway to clear senescent cells, allowing for new muscle cell generation.
Younger muscle cells work harder, and recover faster than older muscle cells because they have higher mitochondria counts which produce energy, greater ATP energy production capacity, and higher glycogen storing capacity. Senactiv® is the first senolytic for enhanced exercise performance and endurance on the market.1, 2, 3, 4, 5, 6, 7, 8, 9
SPORTS NUTRITION
Protein and BCAA formulas, Pre-Workout, Recovery, and Intra Workout Formulas
FUNCTIONAL FOOD & BEVERAGES RTDs
Powdered Drink Mixes, Protein Bars or Baked Goods, Gummies, and Gels
NUTRACEUTICALS
Vitamins and Minerals, Probiotics, Immune Support, Digestive Enzymes, etc.
ANIMAL PRODUCTS
Pet & Livestock Nutritional Foods and Supplements
Highly purified fractions extracted from Rosa roxburghii (fruit) and Panax notoginseng (root).
Clinical dosage: 50mg
1. Improved inflammatory balance of human skeletal muscle during exercise after supplementations of the ginseng-based steroid Rg1. PLOS One. Jan 2015. (3 human trials) doi: 10.1371/journal.pone.0116387. eCollection 2015.
2. Ginsenoside Rg1 supplementation clears senescence-associated β-galactosidase in exercising human skeletal muscle. Journal of Ginseng Research. June 2018. (1 human trial) doi: 10.1016/j.jgr.2018.06.002.
3. Satellite cells depletion in exercising human skeletal muscle is restored by ginseng component Rg1 supplementation. Journal of Functional Foods. April 2019. DOI: 10.1016/j.jff.2019.04.032 (1 human trial)
4. Exercise against aging: Darwinian natural selection of fit and unfit cell inside human body. Journal of Science in Sport and Exercise. June 2019. DOI: 10.1007/s42978-019-0002-y (1 human trial)
5. Aerobic exercise induces tumor suppressor p16ink4a expression of endothelial progenitor cells in human skeletal muscle. Aging. July 2020. https://doi.org/10.1016/j.jgr.2018.06.002 (1 human trial)
6. Oral Rg1 supplementation strengthens antioxidative defense system against exercise-induced oxidative stress in rat skeletal muscle. Journal of the International Society of Sports Nutrition. 2012.
7. Ginsenoside Rg1 protects the liver against exhaustive exercise-induced oxidative stress in rats. Evidence-based Complementary and Alternative Medicine. June 2011. doi.org/10.1155/2012/932165 (in vivo)
8. Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1. Journal of Ginseng Research. April 2021. https://doi.org/10.1016/j.jgr.2021.04.006 (in vivo).
9. Reduced stem cell aging in exercised human skeletal muscle is enhanced by ginsenoside Rg1. Aging. Jun 2021. doi: 10.18632/aging.203176 (1 human trial)
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.