1 min read

BREA, CA – Nuliv Science announced the findings of a new study on its mood and sleep ingredient, Zylaria™. A recent study in the Journal of Biochemistry and Biotechnology examined the effects of three different botanical compositions Xylaria nigripes extract (XE), Xylaria nigripes + Panax notoginseng extract (XPE), and Xylaria nigripes+Panax notoginseng+Cuscuta chinensis extract (XPCE) on γ-Aminobutyric acid (GABA) content, GABA transaminase (GABA-T), Glutamate decarboxylase (GAD), cells viability, and Amyloid-β protein (Aβ) aggregation levels in PC12 neuron cells.  PC12 cells synthesize, store, and release norepinephrine and dopamine.

All three compositions could effectively improve GABA production and also increase the activity of glutamate GAD along with decreased GABA-T activity in PC12 cells in a dose-dependent fashion. Out of the three compositions, the Zylaria™ (XPCE) composition showed the best holistic neuroprotective and GABA-releasing properties than XE and XPE. The researcher observed and suggests that the improvement of GABA levels and strong neuroprotective activity makes these novel compositions (XE, XPE, and XPCE) a potent candidate for supporting insomnia, depression, and various neurological conditions.

Zylaria™ is a research project we’ve been working on for years, evaluating different formulations for a balance of efficacy and serving size. We’re excited to share publicly our latest research findings.” Said Richard Wang, CEO at NuLiv Science. 

The company looks forward to continuing its research and development of Zylaria™ as it is gaining popularity in the market among leading brands for mood and sleep products. 

For more information about NuLiv Science, visit www.nulivscience.com, or stop by booth #4321 at SupplySide West in Las Vegas November 2-3, 2022.


Nuliv Science specializes in the research and development of proprietary and clinically proven nutraceutical ingredients via traditional and Western scientific methods. Since 1997, the company has served our clients’ sourcing and research needs with an emphasis on quality and efficacy. 

Our clientele base, from large MLMs and global sports nutrition brands to natural health practitioners, is as diverse as our ingredient portfolio. NuLiv Science’s experienced research team and network of scientific advisors can help with formulations, efficacy, standardization analytics, and the production of high-potency extracts. 


Josh Beaty, Marketing Director