What Goes Into a Great Supplement? Let’s Breakdown Creatine Absorption, Nutrient Uptake, and Hydration Benefits
In today’s crowded supplement market, true results come from formulas built on creatine absorption, nutrient uptake, and ingredient synergy—not just buzzwords. This episode of In the Mix features Donovan from Centurion Labz as he breaks down their supplement strategy, the real AstraGin benefits, and how they formulate products that deliver.
From creatine absorption to recovery optimization, and from industry trends to transparent ingredient talk—this episode breaks it all down. Donovan also shares how ingredients like AstraGin®, Senactiv®, and Zylaria® are shaping the future of sports nutrition, recovery, and sleep support.
What Makes a Supplement Actually Effective? Centurion Labz Strategy on Creatine Absorption, AstraGin Benefits & Nutrient Uptake
“Not all supplements are created equal” has become a mantra among educated consumers, but what does that mean from a formulator’s perspective? Donovan, National Director of Sales at Centurion Labz, breaks down the supplement formulation strategy behind their best-selling products. According to him, formulating supplements that work starts with understanding how each ingredient interacts within the body—not just in a lab.
While many brands chase trends or flashy branding, Centurion Labz’s supplement strategy is grounded in clinical research, ingredient synergy, and results you can feel. They focus on selecting clinically studied ingredients, maximizing bioavailability through absorption enhancers like AstraGin®, and incorporating performance actives such as Senactiv® to support muscle recovery and ATP production. Each formula is designed to deliver layered benefits—enhancing performance, recovery, sleep, and endurance in real-world conditions.
By working closely with nutraceutical ingredient developers, like NuLiv Science, Centurion Labz ensures its products reflect the latest science in sports nutrition formulation. Donovan emphasizes that staying ahead of the curve means applying time-tested fundamentals with precision and discipline, not just chasing what’s trendy.
He also highlights that effective supplement formulation must account for real-life variables. Factors like hydration status, macronutrient intake, and timing can significantly impact how well a supplement performs. That’s why bioavailability, dosing, and ingredient synergy remain central to every product they develop.s education as a major pillar of the brand’s approach.

Creatine Absorption & AstraGin Benefits: A Supplement Efficiency Breakdown
Creatine is one of the most trusted performance supplements, but many people overlook one key factor: creatine absorption.
Donovan from Centurion Labz explains, “You can take all the creatine you want, but without proper hydration, carbs, or absorption, you’re not getting the full benefit.”
That’s where AstraGin® comes in. This bioavailability booster from NuLiv Science helps improve nutrient uptake, making ingredients like creatine and amino acids more effective. When paired with creatine monohydrate, AstraGin helps deliver those nutrients directly into your muscle cells.
Clinically, AstraGin benefits include:
- Up to 66% more amino acid absorption
- Improved gut lining integrity
- Enhanced glucose and nutrient delivery
Centurion Labz’s supplement strategy includes AstraGin in multiple formulas to ensure every dose counts. The result? Greater supplement efficiency and improvement in creatine absorption—more impact, less waste, and real performance benefits. Learn more about bioavailability and absorption.
Beyond Recovery: Senactiv & the Centurion Labz Supplement Strategy
While absorption is key, so is what happens after the workout. Recovery is where real gains are made, and this is where Senactiv® comes into play.
Senactiv is another trademarked ingredient from NuLiv Science that supports cellular repair and regeneration. Donovan explains that Centurion Labz incorporates Senactiv into their post-workout and performance blends to help:
- Reduce muscle inflammation
- Support ATP production (cellular energy)
- Improve endurance and reduce perceived fatigue
One of Senactiv’s biggest advantages is its ability to support longevity in training. By clearing out senescent cells and promoting healthy mitochondrial function, Senactiv plays a pivotal role in both recovery and active performance.
For high-intensity athletes or weekend warriors alike, recovery isn’t just a luxury—it’s a requirement. This is where Donovan says many brands fall short: “They only think about stimulation. But what about repair? That’s where growth actually happens.”
Senactiv helps bridge the gap, offering athletes a way to train consistently without falling victim to chronic soreness or burnout.
The Centurion Labz Formulation Philosophy
Beyond ingredients, it’s the mindset behind the brand that sets Centurion Labz apart. Donovan explains that they build every product with a clear hierarchy:
- Function first — the product has to work. Period.
- Clinically supported ingredients — like AstraGin, Senactiv, and Zylaria
- No fluff, no fillers — only effective, bioactive doses
- Education and honesty — so consumers understand what they’re taking
The Centurion Labz strategy focuses on maintaining a loyal following while pushing forward into new categories like sleep, cognitive performance, and immune support.
A big part of that philosophy is avoiding unnecessary complexity. Donovan believes that the best formulas are the ones that do a few things exceptionally well—not the ones trying to do everything at once. Each ingredient is chosen for its function, and every blend is built with a specific user goal in mind.
He also highlights the importance of working directly with suppliers. “If you’re not asking questions about your ingredients—where they’re sourced, how they’re processed—you’re leaving quality to chance.”
Supplement Ingredient Trends, Industry Pitfalls & What’s Next for Formulation
As the podcast dives deeper, Donovan offers insight into common mistakes new brands make:
- Under-dosing ingredients to save money
- Choosing trendy actives over clinically studied ones
- Not understanding synergy between nutrients
- Relying too heavily on marketing without matching it with real performance
He also talks about the importance of manufacturer relationships, consistent batch testing, and why transparency is the real differentiator in today’s supplement world.
Looking ahead, Donovan sees continued growth in multi-functional ingredients (like Senactiv supporting both energy and recover, absorption boosters like AstraGin being standard in advanced formulas, sleep/cognitive crossovers with ingredients like Zylaria and formulations focused on longevity, not just short-term pump or energy
In a world where the educated consumer is growing in numbers, Donovan believes brands that take the time to invest in true innovation—not just trend-chasing—will come out ahead.
For more on 2025 supplement market growth and trends, click here: https://nulivscience.com/supplement-market-growth-global-trends-opportunities/

Smarter Supplements Start With Smarter Conversations
This episode of In the Mix goes beyond marketing claims and dives into what it really takes to build a product that delivers on its promise.From ingredient transparency to clinical backing, from gut absorption to sleep quality, Centurion Labz is setting a high bar for what modern supplementation can look like.And more importantly, they’re helping lead a larger shift—where education, performance, and trust are finally being prioritized in the supplement world.
If you’re a brand owner, formulator, athlete, or just someone tired of gimmicks — this conversation is your blueprint for building and choosing supplements that work.
Listen to the full episode of In the Mix on YouTube: https://youtu.be/eB_onjwUduk
Or on Spotify, Apple, and Amazon: https://feeds.buzzsprout.com/2468452.rss
Explore AstraGin, Senactiv, and Zylaria at NuLivScience.com
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