The Effects of AstraGin® on Protein Absorption and Synthesis in Muscles
AstraGin® is a proprietary plant-derived nutraceutical ingredient developed by NuLiv Science. AstraGin® has shown in over a dozen in-vitro studies to improve the absorption of amino acids, peptides, folate, glucosamine and other nutrients in Caco-2 cell, the gold standard used by drug companies to study the absorption of new drugs.
AstraGin® has shown to increase the steady-state absorption rate of arginine, agmatine, β-alanine, citrulline, creatine, leucine, peptides and tryptophan by 67%, 36%, 25%, 45%, 33%, 58%, 41% and 53% respectively, increase curcumin absorption by 92%, increase folate absorption by 50%, increase polyunsaturated fatty acid absorption by up to 100%, increase glucosamine absorption by 23%, increase ATP production in liver by 18%, and reduce intestinal wall inflammation by 73%.
AstraGin® increases the absorption and bioavailability of amino acids and peptides in the bloodstream
Protein plays a crucial role in almost all biological processes, and amino acids are the building blocks of it. AstraGin® increases the absorption of many amino acids and peptides in the gut so more are delivered to the bloodstream to all cells in the body.
AstraGin® increases protein synthesis in muscle
One of the most researched pathways of muscle growth is the mTOR pathway, and leucine activates complex muscle-building pathways via mTOR. AstraGin® has shown to increase intestinal leucine absorption by 58% in 15 minutes, and increases intestinal arginine absorption by 67%, which also triggers the mTOR pathway.
AstraGin® promotes glucose metabolism and mitochondrial functions
AstraGin® inhibits saturated fatty acid absorption while increasing the absorption of polyunsaturated fatty acids from omega-7, flax oil, and fish oil.
AstraGin® regulates appetite
Tryptophan is a precursor of the neurotransmitter serotonin, which acts as an anorexigenic signal in the brain to stimulate satiety. AstraGin® up-regulates peptide absorption by 41% and tryptophan absorption by 53%.
AstraGin® promotes gut health, immune functions, and nutritional profile
AstraGin® has a positive effect on gut health due to its ability to reduce inflammation in the intestinal wall by 73% in vivo, which is beneficial for good bacteria growth and the availability of essential nutrients like vitamin B12 and K.
Have more questions about AstraGin improving protein absorption? Simply contact us.
References
AstraGin® product dossier, sections 6.4-7.4. Stryer L. Biochemistry, 5th edition, Chapter 3: Protein Structure and Function. Giacometti J, et al. Peptidomics as a tool for characterizing bioactive milk peptides. Food Chem. 2017;230:91-98. Anthony JC, et al. Leucine stimulates translation initiation in skeletal muscle of postabsorptive rats via a rapamycin-sensitive pathway. J Nutr. 2000;130(10):2413-2419. Katsanos CS, et al. A high proportion of leucine is required for optimal stimulation of muscle protein synthesis by essential amino acids in the elderly. Am J Physiol Endocrinol Metab. 2006;291(2):E381-387. Li F, et al. Ginsenoside Rg1 prevents starvation-induced muscle protein degradation via regulation of AKT/mTOR/FoxO signaling in C2C12 myotubes. Exp Ther Med. 2017;14(2):1241-1247.
