Verbasnol verbascoside is NuLiv Science's proprietary verbascoside produced by a proprietary extraction technology.

  • Validated by HPLC as a true verbascoside [a caffeoyl phenylethanoid glycoside (C29H36O15)]
  • A well-studied multipotent antioxidant for topical and oral skin applications


Verbasnol is NuLiv Science's proprietary verbascoside (a caffeoyl phenylethanoid glycoside (C29H36O15)) extracted from Rehmannia glutinosa by a proprietary extraction technology. Verbasnol has been validated as a true verbascoside by HPLC chromatography.

Verbascoside has shown to be effective for :

  • Anti-Aging*
  • Antioxidant Skin Replenishment
  • Anti-Inflammatory*
  • Anti-Oxidant
  • Collagenase Inhibitor*
  • Sebum Regulating*
  • Tyrosinase Inhibitor*


Propionibacterium acnes (P. acnes) is associated with acne lesions and leads to cutaneous inflammation. Verbascoside has anti-acne activity by inhibiting P. acne growth. Verbascoside has shown to decrease the pro-inflammatory chemokine IL-8 expression to exert anti-inflammatory activity on skin cells.

Verbascoside inhibits Malassezia furfur, a lipophilic yeast, growth that is implicated in numerous skin infections, including pityriasis versicolor, seborrheic and atopic dermatitis, dandruff and folliculitis.

Verbascoside exerts a remarkable antioxidative property by scavenging the free radical species that is implicated in oxidative stress in human skin aging. Verbascoside also inhibits the production of tyrosinase that catalyzes the production of melanin to darken the skin. 

Verbascoside inhibits the 5α-reductase activity of skin sebum production to control androgen homeostasis in human skin.



Solubility: Soluble in water
Color: Off white
Odor: Characteristic
Taste: Slightly bitter
Appearance: Fine granular powder
pH: ≤5% (1g in 100mL water)
Shelf life: 36 months
Preservatives: None

A Further Look at Verbasnol™

Iridoids are a type of phytonutrient naturally produced by plants to protect them from the elements. They help to protect the plant from being burnt, eaten, or overtaken by bacteria or microorganisms. Imagine you were a newly grown plant. You would have to overcome insects, harsh weather, fungus, and anything else nature could throw at you. You would need to develop a way to protect yourself. That is the role of these iridoids.

Verbascoside is a specific iridoid that can be extracted from specific plants and can be potentially used to benefit the health of humans in a similar way.

One way in which verbascoside helps plants is by protecting them from harmful UV damage from the sun. In humans, UV radiation can lead to sunburn, darkening of the skin, premature skin aging, or more serious complication with continued exposure.

One of the most noticeable effects of UV radiation is premature aging of the skin. This could include dryness, wrinkles, sagging, loss of elasticity, and increased pigmentation (or dark spots).

The way verbascoside can help is through its antioxidant abilities. Antioxidants have been found to aid in problems related to skin aging as well as assisting in UV protection. According to some researchers, qualifications for sunscreens themselves include antioxidant ability in addition to UV protection.

Antioxidants like verbascoside could provide benefit as a natural UV protectant, help reduce the appearance of dark spots, and improve the bright appearance of the skin.

Verbasnol has also shown in studies to assist in the appearance and amount of skin blemishes by helping to regulate sebum production or the sticky oil produced by the skin that can lead to blemishes.

Verbasnol is a verified verbascoside extracted from the Rehmannia glutinosa plant. According to verbascoside research, Verbasnol may improve the appearance of dark spots, as well as the overall bright appearance of the skin.* Verbasnol may also help to replenish the skin's antioxidants, as well as potential improvements in the appearance on skin blemishes.

Verbasnol is one of the few antioxidants that thrives in an acidic environment, meaning it could do well as an internal beauty product or paired with acidic ingredients.


Clear skin and UV protection

This highly effective protectant functions in Rehmannia glutinosa to fight against physical, environmental, and microbial harm.