The Science Behind Verbasnol™:
Associated Effects Based on Research Findings
In research studies, verbascoside has shown to be effective for:
- Collagenase Inhibitor*
- Sebum Regulating*
- Tyrosinase Inhibitor*
In a study on human fibroblast cells (the cells that comprise your top layer of skin), verbascoside “possessed significant photoprotective activities, reducing MMP and IL-6 levels while improving type-I procollagen synthesis”.
How Verbascoside Works
Propionibacterium acnes (P. acnes) is associated with acne lesions and leads to cutaneous inflammation. Verbascoside has anti-acne activity by inhibiting P. acnes growth. Verbascoside has shown to decrease the pro-inflammatory chemokine IL-8 expression to exert anti-inflammatory activity on skin cells.
Furthermore, verbascoside may inhibit Malassezia furfur (a lipophilic yeast) growth that is implicated in numerous skin irritations, including pityriasis versicolor, seborrheic and atopic dermatitis, dandruff and folliculitis.
Verbascoside exerts a remarkable antioxidative property by scavenging the free-radical species that are implicated in oxidative stress in human skin aging. Verbascoside also inhibits the production of tyrosinase that catalyzes the production of melanin to darken the skin. Verbascoside inhibits the 5α-reductase activity of skin sebum production to control androgen homeostasis in human skin.
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